Small molecule NMR in pharmaceutical sciences

Nmr Analysis of Protein-small Molecule Interactions

INTRODUCTION Advances in NMR technology over the last 20 years have made information on solution structures of proteins increasingly available. High-resolution solution structures of proteins as large as 20-25 kDa are tractable in most cases, and recent advances allowed Kay to solve the structure of an 82 kDa protein. These advances in NMR analysis of protein structure have made possible the st...

Mass spectrometry for small molecule pharmaceutical product development: a review.

Developing a pharmaceutical product has become increasingly difficult and expensive. With an emphasis on developing project knowledge at an earlier stage in development, the use of information-rich technologies (particularly MS) has continued to expand throughout product development. Continued improvements in LC/MS technology have widened the scope of utilizing MS methods for performing both qu...

Education of Pharmaceutical Sciences in Iran

Education of Pharmaceutical Sciences in Iran

Impact of surface tension in pharmaceutical sciences.

Surface chemistry has a large influence in many industries. In the life sciences, surface area is gaining importance in the characterization of materials during their development, formulation and manufacturing. The chemical activity, adsorption, dissolution, and bioavailability of a drug may depend on the surface of the molecule. In order to meet manufacturing challenges and develop new and bet...